This Southern Five Layer Beef Casserole combines seasoned ground beef, rice, vegetables, and cheese in a hearty, flavorful dish. Each layer brings together classic Southern ingredients for a comforting meal thatโs easy to prepare and perfect for feeding a crowd. Enjoy this simple, delicious casserole thatโs sure to become a family favorite. Keywords: southern five layer beef casserole, beef casserole with rice, layered casserole, ground beef dinner, southern comfort food.